One in five subjects with normal thyroid ultrasonography has altered thyroid tests

Enlarged thyroid gland with normal thyroid function tests.

A 41-year-old woman had a 1to 2-cm asymptomatic thyroid mass, which had been monitored by an endocrinologist for several years with serial sonography. Noting that it had enlarged in the face of normal thyroid function tests, the endocrinologist ordered a fine-needle aspiration biopsy, which showed a cellular follicular lesion. Although some of the nuclear changes seen in papillary carcinoma wer...

How Are Thyroid Function Tests Altered by Thyroid Replacement Medications?

Thyroid hormones and TSH in normal subjects.

Serum T4, 13, Free-T4, and TSH levels were estimated in 70 normal subjects (33 males and 37 females) using radioimmunoassay techniques. There was no significant difference in the levels of various hormones between the two sexes. The horñional, pattern of present series was quite similar when compared with other studies. Ihe results showed that the levels of various thyroid hormones and TSH were...

Thyroid hormone replacement one day before 131I therapy in patients with well-differentiated thyroid cancer

Objective: The current study aimed to determine the efficacy of radioiodine-131 (131I) ablation therapy with thyroid hormone replacement one day before 131I administration in patients with well-differentiated thyroid cancer (DTC). Methods: This retrospective study included 29 patients who underwent 131I therapies twice for DTC during 6-12 months.  Since all the patients obviously had residual l...

Normal Thyroid Function Tests Following Discontinuation of Levothyroxine in Hypothyroid Iodine Deficient Individuals

SUMMARY In 28 school children with primary hypothyroidism due to iodine deficiency, 100 µg levothyroxine (L-T4} was administered for nine weeks and resulted in normalization of serum T4, T3, and TSH. Five months after withdrawal of L-T 4 , thyroid function was normal in the majority of subjects. Serum T4 was 8.6±2.3 µg/dl ; T3, 156±2.3 ng/dl; and TSH, 6.9± 12.7 µU/ml. Only one subjects showed ...